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How Mental Health Impacts the Nervous System

by May 13, 2025

The Deep Connection Between Mental Health and the Nervous System

Mental health is often viewed through the lens of emotions and behavior—but beneath those experiences lies a complex biological system that is significantly affected by our mental state: the nervous system. Understanding how mental health impacts the nervous system not only deepens our compassion but also empowers us to take more holistic approaches to healing.


What Is the Nervous System?

The nervous system is your body’s command center. It consists of two main parts:

  • Central Nervous System (CNS): Includes the brain and spinal cord. It processes information and dictates responses.

  • Peripheral Nervous System (PNS): Connects the CNS to the rest of the body, including muscles and organs.

Together, these systems manage everything from breathing and digestion to emotions and cognition.


Mental Health and the Stress Response

One of the most direct ways mental health affects the nervous system is through the stress response. When we experience chronic stress, anxiety, or unresolved trauma, the nervous system reacts in a few key ways:

  • Activation of the Sympathetic Nervous System (SNS): This is the “fight or flight” response. It increases heart rate, elevates cortisol levels, and prepares the body for perceived danger—even when no real threat is present.

  • Suppression of the Parasympathetic Nervous System (PNS): The PNS is responsible for “rest and digest” functions. Chronic mental stress inhibits this calming system, leading to ongoing tension and poor health recovery.


How Mental Health Conditions Alter Brain Function

Mental health disorders such as depression, anxiety, PTSD, and bipolar disorder have a biological footprint in the brain and nervous system:

  • Depression is associated with reduced activity in the prefrontal cortex and imbalances in neurotransmitters like serotonin and dopamine.

  • Anxiety disorders can lead to overactivation of the amygdala (the brain’s fear center), causing heightened threat perception.

  • Trauma may lead to dysregulation of the autonomic nervous system, making individuals either hyper-aroused (jumpy, on edge) or hypo-aroused (numb, detached).

These neurological changes can influence memory, decision-making, energy levels, and even immune function.


The Body Keeps the Score

As psychiatrist Dr. Bessel van der Kolk famously stated, “The body keeps the score.” Mental health struggles are not “just in your head”—they affect physical health too. Prolonged mental distress can lead to:

  • Digestive issues

  • Chronic fatigue

  • Headaches and muscle pain

  • Sleep disturbances

  • Weakened immune responses

These are all signs of a nervous system that’s out of balance due to mental strain.


Supporting Your Nervous System Through Mental Wellness

Fortunately, the nervous system is adaptable, a concept known as neuroplasticity. Here are ways to support both mental health and nervous system regulation:

  • Therapy (especially CBT, EMDR, and somatic approaches)

  • Mindfulness and meditation

  • Regular physical activity

  • Adequate sleep and nutrition

  • Breathing exercises and vagus nerve stimulation


Final Thoughts

The relationship between mental health and the nervous system is both intricate and powerful. When our mental health suffers, so does our body. But with the right tools, support, and understanding, we can calm an overactive nervous system and restore emotional balance.

Mental health care is nervous system care—and both are essential to living a full, resilient life.